The Medication

Bupropion

First month: $8 $45/month
+ one time $15 online physician visit

Bupropion is a smoking cessation aid that can help reduce nicotine cravings and withdrawal symptoms. For smoking cessation, bupropion is prescribed for a 12-week course.

The Rx

Curb cravings with prescription medication.

Curb cravings

Prescription bupropion helps curb cravings and make nicotine less pleasurable.

12-week program

Studies show best results from bupropion with at least 7 weeks of use, and even better results with 12 weeks of use.

Access to a doctor

Ask your doctor questions any time through your My Ro account.

From our community

Quitter testimonials

In only 4 Days I didn’t feel the urge to pick up a cigarette or take a pull of my e-cigarette…at all! It’s been two weeks now and I am still smoke-free, cigarette free, and e-cigarette free.
Justin H
Zero Quitter, Boston
I went from 15 years smoking, to 41 days not smoking and that’s huge. And I really thank Zero for that.
James N
East Stroudsburg, PA
I'd still be smoking without Zero, plain and simple. The medication, gum, app combo helped me quit for good.
Mike S
Zero Quitter, New York, NY
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The details

Bupropion medical information

About Bupropion

Bupropion is a smoking cessation aid that can help reduce nicotine cravings and withdrawal symptoms. For smoking cessation, bupropion is prescribed for a 12-week course. Learn more about bupropion, its potential benefits, and its potential side effects. Bupropion Medical Facts

How does it work?

The action of bupropion is not fully understood, but we know bupropion blocks the neurotransmitters dopamine and norepinephrine from being reabsorbed, which means they hang around and work longer.

Bupropion seems to affect these these two important neurotransmitters in a way that is similar to nicotine, which can decrease your withdrawal symptoms when you are trying to quit. Bupropion also weakly blocks the nicotine receptor (the place on a nerve cell where a chemical lands to transmit its message), which makes smoking less appealing. This helps prevent relapse when former smokers are trying to make their new habit stick.

How is it used?

Bupropion should be started at least one week before you quit smoking. Bupropion should be taken once daily for the first 3 days, to allow your body to adjust. It should then taken twice daily for the 12 weeks.

What are the possible side effects?

The most common side effects of bupropion include: agitation, dry mouth, insomnia, headache/migraine, nausea/vomiting, constipation, tremor, dizziness, excessive sweating, blurred vision, tachycardia (rapid heart rate), confusion, rash, hostility, cardiac arrhythmia (irregular heartbeat), and auditory disturbance.

Bupropion is generally very safe, but all medicines have the potential for causing side effects. Rarely, these can be serious, and you need to know about them.

Bupropion has a black box warning about a potential for increased risk of suicidal thoughts and behaviors. This increased risk is seen in patients up to age 24. It’s important to remember that bupropion is primarily used as an antidepressant, and people with depression are at higher risk of suicidal thoughts and behaviors. However, it’s possible that bupropion taken for other reasons, like smoking cessation, might also have this increased risk.

Learn more about bupropion, its potential benefits, and its potential side effects here.

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Frequently Asked Questions

Still didn’t find your answer? Please reach out to our care team at care@ro.co

What if I don’t want a prescription?
No problem. The way you choose to quit is entirely up to you, and you can select this preference during your online doctor visit.

With that being said, multicomponent therapy has been shown to be superior for successful quitting compared to single component therapy.
Are there any side effects of bupropion?
According to the Physician’s Desk Reference (PDR) common reactions may include “agitation, dry mouth, insomnia, headache/migraine, nausea/vomiting, constipation, tremor, dizziness, excessive sweating, blurred vision, tachycardia (rapid heart rate), confusion, rash, hostility, cardiac arrhythmia (irregular heartbeat), and auditory disturbance.
Is this medication sold only by Zero?
Zero is the only online smoking cessation solution that uses multicomponent therapy to help you quit smoking. Part of this treatment includes the use of bupropion which can be prescribed by other doctors and sold by other pharmacies.
Can I use my insurance?
Not at the moment, but hang tight! We are working to allow for insurance coverage in the near future.

This medication may be covered by insurance though (inclusive of Medicaid and Medicare) when sold by other providers.

Other ways to quit

Our product offerings

Doctor recommended treatment

Bupropion + Gum

First month: $50 $87/month
+ one time $15 online physician visit
The combination of prescription bupropion and nicotine gum can increase your chances of successfully quitting by over 3x compared to cold turkey. *
Learn more Get Bupropion + gum

Nicotine replacement therapy

Nicotine gum

First month: $5 $42/month
Nicotine gum is a nicotine replacement therapy (NRT) that can help reduce withdrawal symptoms like restlessness, irritability and anxiety.
Learn more Get the gum

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